...缺陷性慢病毒 自杀基因 小鼠 异基因骨髓移植 脂质体 【文 摘】目的探讨复制缺陷性慢病毒介导的胞嘧啶脱氨酶(cytosine deaminase，CD)和胸苷激酶(thymidine kinase，TK)双自杀基因在异基因骨髓移植(allo-BMT)时...
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目的：探讨亚叶酸钙(CF)联合5氟胞嘧啶(5 FU)对转染胞嘧啶脱氨酶(CD)基因的直肠癌细胞的杀伤作用。
Objective to study antitumor effect of calcium folinate (CF) and 5 fluorocytosine (5 FU) on rectal carcinoma cells transfected with cytosine deaminase (CD) gene.
胞嘧啶脱氨酶是一种能够将叫做5 -氟胞嘧啶(5 - FC)的药物转化为活跃的化疗药物5 -氟尿嘧啶的酶，但这种情形只发生于干细胞的紧邻。
This is an enzyme that converts a drug called 5-fluorocytosine (5-fc) into an active chemotherapy drug, 5-fluorouracil (5-fu), but only in the immediate vicinity of the stem cell.
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