一种被称为缺氧诱导因子蛋白的特殊蛋白,控制帮助低氧条件下生存的基因。低氧的区域通常产生肿瘤的快速生长。
A specific protein, called the hypoxia-inducible factor protein, controls genes that help calls survive under low-oxygen conditions. Areas of low oxygen are common for fast-growing tumors.
目的:研究氯化钴模拟化学缺氧条件下,缺氧诱导因子1相关肽(BW8)对PC 12细胞损伤的影响。
Objective: to investigate the protective effect of the hypoxia-inducible factor-1 relevant peptide (BW8) on chemical hypoxia-induced injury in PC12 cells.
缺氧诱导因子- 1是近几年研究较多的转录因子,它可使肿瘤在生长侵袭过程中适应缺氧应激,也为肿瘤治疗提供了新思路。
Hypoxia-induced factor-1 is a transcription factor which is widely studied in recent years. It helps progressing tumors adapt to hypoxia stress and also provides a new clue for tumor therapy.
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