结论：在丙戊酸治疗药物监测中，要关注影响丙戊酸血药浓度的因素，确保患者用药安全有效。
CONCLUSION: in therapeutic drug monitoring of valproate, it should be concerned about the impact factors of valproate concentration to ensure the safety and efficacy in patients.
目的：采用反相高效液相色谱法测定两性霉素B的血药浓度，用于该药的治疗药物监测。
OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.
医生先通过纳米粒确定药物是否到达了理想的作用部位，再经作用部位药物浓度监测，评价药物是否对病灶起到治疗作用。
Using the nanoparticles, a physician can confirm a drug has reached the desired location, measure the amount of drug at the site, and later check to see if the drug has affected the disease.
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