本发明公开了一种表达胶质源性神经营养因子的慢病毒载体及其用途,属于医学生物技术领域。
The invention discloses a lentiviral vector for expressing the glial cell line-derived neurotrophic factor and applications thereof, which belong to the field of medical biotechnology.
结论成功构建了带有大鼠bmp - 7基因的慢病毒载体,并实现其在HSC - T6的稳定高表达。
Conclusion Lentiviral vector carrying BMP-7 gene has been successfully constructed and maintains high expression in HSC-T6 cells.
目前应用的病毒载体主要有逆转录病毒载体、腺病毒载体、腺病毒相关病毒、慢病毒载体、单纯疱疹病毒载体等。
At present, the mainly applied virus vectors are retroviral vector, adenovirus vector adenovirus-associated virus slow virus vector, herpes simplex virus vector and so on.
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