结论骨巨细胞瘤中的多核巨细胞可能是由单核基质细胞融合而成,ADAM12基因参与了这一融合过程。
Conclusion Multinucleated giant cells probably originated from the fusion of mononuclear stromal cells and ADAM12 may participate in the fusion process.
组织细胞样细胞可演变为泡沫细胞和多核、单核的瘤巨细胞,另见少量未分化间叶细胞。
The histiocyte-like ce- lls may be transformed into foamy cells, mononucleated or multinucleated tumor giant cells. Undifferentiated mesenchymal cells were rarely seen.
CPE的主要表现为细胞的折光度降低、细胞圆缩、颗粒变性、细胞融合而形成多核巨细胞。
The main expressions of CPE consisted in decreased cell diopter, rounding reduced cells, modified particles and formation of multinuclear large cells due to cell fusion.
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