目的:鉴定自制的抗CD3-抗胶质瘤双特异性抗体(双抗)的双向结合能力,测定其免疫活性及其对T淋巴细胞的作用。
Objective: To study bidirectional binding ability and immunoactivity of anti-CD3/anti-glioma bispecific antibodies(BsAb) , and to study its effect on T lymphocytes cells.
结论建立的双抗体夹心elisa检测MP抗原具有快速、简便、灵敏度高、特异性强等优点。
Conclusions Antibody-sandwich ELISA for detection of mp antigen is simple, rapid, sensitive and specific.
还提供了包含本发明抗体的免疫偶联物、双特异性分子和药物组合物。
Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided.
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