最常使用化学诱导药物是亚硝胺类的二乙基亚硝胺(diethylnitrosamine,DEN),然而DEN诱导的鼠肝细胞癌多为EdmondsonⅠ级和Ⅱ级,转移率很低,与人肝癌转移复发率较高的情...
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最常使用化学诱导药物是亚硝胺类的二乙基亚硝胺(diethylnitrosamine,DEN),然而DEN诱导的鼠肝细胞癌多为EdmondsonⅠ级和Ⅱ级,转移率很低,与人肝癌转移复发率较高的情...
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根据Solt-Farber方法, 以2 g/L的二乙基亚硝胺(diethyl nitrosoamine, DENA)制备肝癌模型, 15 wk后停药. 根据大鼠肝癌的诊断标准由两位病理医生进行病理分型[6].
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在二乙基亚硝胺(DENA)诱发大鼠肝癌过程中,维生素k依赖性羧化酶活性呈现先降低、后升高的现象。
During hepatocarcinogenesis induced by diethylnitrosamine (DENA) in rats, a period of decreased vitamin K-dependent carboxylase activity was observed followed by an increased period.
本文观察了用日本血吸虫与二乙基亚硝胺诱发家兔肝癌的实验结果。
This paper reported the results of the experimental liver carcinoma induced by Schistosoma japonicum and diethylnitrosamine(DEN)in rabbits.
本组对二乙基亚硝胺所诱导的大鼠原发性肝癌组织中的组氨酸酶活性及酶蛋白表达进行了研究。
The catalytic activity of histidase and the expression of the enzyme protein were investigated in rat hepatomas induced by diethylnitrosamine.
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