Objective: The aim of study was to explore the relation between LEP level in blood serum、LEP receptor variation 、blood lipid、diet、breeding, etc and breast cancer, and to find out the risk factors of beast cancer Methods: A case-control study was used.
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目的探讨血清瘦素水平，瘦素受体变异与乳腺癌发生的关系。
Objective To explore the relations between blood LEP level, LEP receptor variation and breast cancer.
结论血清瘦素水平高，瘦素受体变异为乳腺癌发生的可疑危险因素。
Conclusion the high blood LEP level and the mutation of the LEP receptor may be risk factors of breast cancer.
结论：瘦素受体基因外显子4中519位点变异不是肥胖症的遗传因素。
CONCLUSION: Variation of exon 4 in LEPR gene at site 519 is not a genetic factor of obesity.
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