目的通过对星形细胞瘤水肿区和瘤体区的组织学观察，探讨其不同区域的血管生成，并观察拟态血管的形态学基础。
Objective to study angiogenesis patterns in the edematous area and the center of human astrocytomas by histological observation, and to reveal histological basis of vasculogenic mimicry.
肿瘤细胞表达基质金属蛋白酶类物质和勃附分子说明了恶性黑色素瘤组织存在血管生成拟态形成的物质基础。
TIMP, MMP-2,1C AM were secreted by the tumor cells can boost the adhere of tumor cells and matrix remold and turn into the substance base of vasculogenic mimicry .
结论在胶质瘤中存在血管生成拟态现象，且恶性度越高形成拟态血管能力越强。
Conclusion Vasculogenic mimicry exists in glioma, and the higher invasive glioma exists more VM.
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