...复发患者的III期研究(RESPOND-2)结果表明:Boceprevir联合SOC显著增加患者持续病毒学应答率(Sustained Virological Response,SVR),Boceprevir+SOC的三联治疗耐受性良好,但与SOC组相比,三联治疗组贫血与味觉障碍的发生...
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...者的III期研究(RESPOND-2)结果表明:Boceprevir联合SOC显著增加患者持续病毒学应答率(Sustained Virological Response,SVR),Boceprevir+SOC的三联治疗耐受性良好,但与SOC组相比,三联治疗组贫血与味觉障碍的发生...
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结束时的病毒学应答率 end of treatment response ; ETR
在两项试验中,持续的病毒学应答率为79%和80%,相比标准治疗方案,即长效干扰素联合利巴韦林的应答率50%更高。
The sustained virologic response rate was 79% and 80% in two studies, which was higher than the response rate of 50% with the standard of care with peginterferon plus ribavirin.
持续病毒学应答可以降低肝硬化和肝病并发症的发生,降低肝癌(肝细胞性癌)和死亡的发生率。
Sustained virologic response can result in decreased cirrhosis and complications of liver disease, decreased rates of liver cancer (hepatocellular carcinoma), and decreased mortality.
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