...： 正可逆的乙酰化修饰是真核生物染色质改构的重要机制之一,与转录调控密切相关,由组蛋白乙酰转移酶(histone acetyltransferases,HATs)和去乙酰化酶(histone deacetylases,HDACs)所催化。
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由组蛋白乙酰基转移酶 histone acetyltransferases
组蛋白乙酰化和去乙酰化由一对功能相互拮抗的蛋白酶——组蛋白乙酰基转移酶和组蛋白去乙酰化酶负责。
The acetylation and deacetylation of histone is charged by a pair of protea se with antistatic function on each other, which are histone transacetylase and histone deacetylase.
组蛋白乙酰化与基因转录等生物效应有密切的关系，组蛋白乙酰化主要是由组蛋白乙酸转移酶催化的。
Histone acetylation has a close relation with some biological effects such as gene transcription, and is catalyzed by histone acetyltransferases.
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