该制剂适用药物范围广，尤其适合两亲性差或生物大分子药物。

The preparation has wide application range of drugs and is particularly suitable for drugs with poor amphipathicity or the biological macromolecules.

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这些联用技术的应用将为生物大分子药物的研究开发开拓广阔的前景。

The applications of these new combined techniques will open up broad prospect for the research and development of biomacromolecule drugs.

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综述了喜树碱及其衍生物的小分子、大分子和轭合物前药的研究进展，为新型喜树碱前药的合理药物设计提供一定参考。

The recent progress in low molecular, high molecular and couplet prodrugs of CPTs was reviewed in classified manner, provide a reference for the design of prodrugs of CPTs.

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The big Pharma hasn't really done research for years but then he married in the biotech area and therefore biotech companies aren't that well run but they spent a great deal in research for the large molecule drugs.

大型制药企业已经很多年没有做过相关研究,但它却与生物技术领域合作,因此导致众多生物技术公司经业绩下降,但生物技术公司在大分子药物的研究上,却投入了很多。

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