目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。

Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.

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研究表明，在病毒感染过程中，狂犬病毒糖蛋白及基质蛋白均能诱导宿主细胞发生凋亡，有许多凋亡分子参与这个过程并起着作用。

It has been found that the ra - bies virus glucoprotein and matrix protein can induce cell apoptosis during the infection. Many cell apoptotic molecules are involved in the process.

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