供体特异性脾细胞输注 donor specificspleen cell tranfusion
目的观察不同脾细胞亚群强化骨髓细胞输注调节特异性免疫状态的效应，并探讨其可能机制。
To investigate the effect and the mechanisms of subtypes of splenocytes improving the regulatory effect on specific immune response following donor bone marrow infusion.
通过二聚体染色和HBV肽刺激后的细胞内细胞因子染色测定肝和脾中HBV特异性CD 8 + T细胞的频率和功能。
The frequency and functionality of HBVspecific CD8 + t cells in the liver and spleen were determined by dimer staining and intracellular cytokine staining after stimulation with HBV peptides.
结论单一胸腺或腹腔内注射同种脾细胞可以诱导新生大鼠的特异性免疫耐受。
Conclusions Intrathymic or intraperitoneal inoculation of allogeneic cells in a neonatal recipient with an immature system can produce donor specific tolerance to a subsequent graft.
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