目的：探讨5-HT3型受体特异性拮抗剂奥丹西隆对吗啡诱导的条件性位置偏爱（CPP）效应的影响及其可能机制。

OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.

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由于M受体拮抗剂缺乏对受体的选择性和对组织的特异性，限制了其临床应用。

However, the lack of receptor subtype selectivity or organ specificity of m receptor antagonists limited their clinical application.

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