采用杂交瘤技术制备人源性单克隆抗体存在许多困难，90年代初期出现了抗体库技术，为抗体的制备提供了新的途径。

But it is difficult to make humanized monoclonal antibody with hybridoma technique. Antibody library technique coming forth in the early 90s provides the new method to get the antibody.

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同时，利用此重组蛋白为抗原，制备了小鼠组织因子的小鼠源功能阻断性单克隆抗体，在血浆凝集实验中证明其对小鼠组织因子的活性有明显抑制作用。

Using this recombinant mTF as immunogen, a murine monoclonal function-blocking antibody to mTF was also generated, which can inhibit mTF-initiated plasma clotting in vitro.

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