...文网 关键词】 清肝活血方; 清肝方; 活血方; 酒精性肝疾病; 肿瘤坏死因子α; 大鼠 [gap=3133]Keywords: Qinggan Huoxue Recipe; Qinggan Recipe; Huoxue Recipe; alcoholic liver disease; tumor necrosis factor..
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目的：观察清肝活血方对酒精性肝病大鼠乙醇代谢关键酶基因表达的影响。
Objective: To observe the effect of Qinggan Huoxue Decoction on gene expression of key enzyme about alcohol metabolism of Wistar rat with alcoholic liver disease (ALD).
结果：清肝活血方各剂量组能显著降低酒精性肝纤维化大鼠血清ALT、AST水平（P<0.05）；
Results:The levels of ALT, AST in blood have been decreased obviously in QGHXR groups(P<0.05).
清肝活血方并可降低肝纤维化标志物、细胞因子水平，抗肝脏脂质过氧化损伤，较明显改善脂肪肝程度。
QGHXR also showed effects in lowering levels of liver fibrosis markers and cytokines, alleviating the anti-lipid superoxidation damage in liver, and could markedly improve the degree of fatty liver.
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