Conclusion La could decrease CaM activity,CaMK IV and CREB phosphorylation,c-fos,c-jun and egr1 mRNA expression in the hippocampal CA3 area and therefore cause learning and memory impairment of rats.
结论镧可通过降低海马CA3区CaM活性和CaMK IV、CREB磷酸化以及c-fos、c-jun和egr1基因转录水平,从而损害大鼠的学习记忆能力。
参考来源 - 镧对大鼠海马CA3区cAMP应答元件结合蛋白磷酸化和及刻早期基因表达的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
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