CHIP的特殊结构特征使其成为沟通分子伴侣与泛素-蛋白酶体通路之间的桥梁，是蛋白质量控制系统的重要中介分子。
The special characteristics of CHIP make it become the bridge of molecular chaperone system and ubiquitin-proteasome pathway.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、 基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
目的探讨泛素-蛋白酶体通路(UPP)在实验性视网膜脱离(RD)中对视网膜细胞凋亡的调控作用。
Objective to investigate the role of ubiquitin-proteasome pathway (UPP) in the regulation of retinal cell apoptosis after experimental retinal detachment (RD).
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