河豚毒素(tetrodotoxin,TTX)是鲀鱼类(俗称河豚鱼)及其它生物体内含有的一种生物碱。该毒素经腹腔注射对小鼠的LD50为8μg/kg。曾一度被认为是自然界中毒性最强的非蛋白类毒素。河豚毒素的化学性质稳定,一般烹调手段难以破坏。中毒后也缺乏有效的解救措施。河豚毒素纯品的国际市场价每克可达21万美元,具有极高商业价值。
探讨河豚毒素(TTX)的中毒机理及临床TTX中毒的有效救治措施。
The intoxication mechanism of tetrodotoxin (TTX) and its effective treatment methods were introduced in this article.
ELISA法由于其测定程序简便易行,速度快,灵敏度高,在河豚毒素的定量检测以及在预防河豚鱼中毒方面具有广泛的应用前景。
Because ELISA is an easy-handled, rapid and highly sensitive method, it would play an important role in quantitatively detecting tetrodotoxin and effectively regulating poisonous puffer fishes.
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