目的探讨凝血酶对体外培养的原代大鼠脑微血管内皮细胞(bmvec)的损伤作用及凝血酶抑制剂水蛭素的保护作用。
AIM to investigate the apoptotic effect of thrombin on brain microvascular endothelial cell (BMVEC) of cultured rat, and the protective effect of hirudin, an inhibitor of thrombin.
目的探讨凝血酶对脑组织损害的机制，及凝血酶抑制剂水蛭素和尼莫地平对其的影响。
Objective To investigate the mechanism of brain injury caused by thrombin and the intervention effect of hirudin and nimodipine.
作为直接凝血酶抑制剂，重组水蛭素在临床上的应用已越来越重要。
As a direct thrombin inhibitor, recombinant hirudin (r-hirudin) has played an important role in clinical use.
应用推荐