CHMP同时指出在步行距离评价等方面对患者的受益很有限，相应的试验有一系列缺陷。

The CHMP also noted that the medicine had only been shown to have a limited benefit for patients, measured in terms of walking distance, and the studies assessed had a number of weaknesses.

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结果：治疗后，试验组患者六分钟步行距离明显延长，LVEF明显提高，BNP及CRP均显著下降。

Results: in experiment group, the six minutes walk distance was obviously longer, LVEF was notably increased, BNP and CRP were significantly lower.

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