生命科学 关键词：核移植； 核重编程； 治疗性克隆； 表遗传标记 [gap=1858]Key words : nuclear transfer; nuclear reprogramming; therapeutic cloning; epigenetic modification
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一般来说，颗粒细胞作为核供体最易被核重编程。
In general idea, cumulus cell is the best nuclear donor cell for reprogramming.
但是核重编程仍是核移植技术的瓶颈，制约了重构胚胎干细胞的研究。
However, nuclear reprogramming, which stands in the way of reconstructed embryo stem cell research, is still a bottleneck in the procedure of nuclear transfer.
在这里，我们调查的，是由体细胞突变引起的肿瘤细胞的细胞核，能被后生重编程进入正常组织的可能性。
Here, we investigate the possibility of whether a tumor cell nucleus, in which transformation is caused by somatic mutation, can be epigenetically reprogrammed into normal tissues.
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