MeSH主题词 核受体辅活化子(Nuclear Receptor Coactivators). 辅酶A(Coenzyme A).
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目的研究设计、合成的基于富含脯氨酸核受体辅活化子(proline-rich nuclear receptor coactivator protein,PNRC)的抗RasPDT融 ..
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脯氨酸核受体辅活化子 proline-rich nuclear receptor coregulatory protein ; proline-rich nuclear receptor eoactivator protein ; PNRC
结果该质粒有正确的阅读框，其表达蛋白不具有自主转录激活作用，与已知核受体辅活化子PNRC有明显的相互作用。
Results The protein expressed by the plasmid which had a correct reading frame, had no transcriptional activation and could interact with a known coactivator PNRC.
大多数雄激素非依赖性前列腺癌均高表达AR和核受体辅活化子、如转录中间因子2（TIF-2），ARA24、PIAS、类固醇受体辅活化子-1（SRC-1）等有力地支持了这个假说。
The "superactive AR"hypothesis was supported by the fact that the majority of AIPC expresses high level of AR and nuclear receptor(NR) coactivators, such as TIF-2, ARA24, PIAS, SRC-1.
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