研究发现,SO_2及其衍生物可引起人外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变、姊妹染色单体交换及微核的形成。
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
本文主要对辐射诱发染色体畸变和微核的形成与细胞分裂周期的关系作了综述和分析,并对微核细胞率作为辐射损伤的细胞学指标进行了评价。
This paper reviewed the relationship between chromosomal aberrations at the different stages of mitotic cycle and the mechanism of chromosomal aberrations and micronuclei induced by radiation.
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