这对我来说是最重要的事情。

It's a matter of the greatest importance to me.

《牛津词典》

记住，友谊是你生命中最重要的事情。

Remember that friendship is the most important thing in your life.

youdao

洗手是人们保持健康所能做的最重要的事情之一。

Hand washing is one of the most important things people can do to keep healthy.

youdao

That's sort of what that's like, but the really important thing is what's the worst thing that can happen.

这和我们说的有点相像，但是真正重要的事情是,可能发生的最坏的事情是什么。

耶鲁公开课 - 金融市场课程节选

And I think personally, I think that's perhaps the most important thing when learning a new language

而且我个人认为，也许这就是学习新语言时最重要的事情，

留在记忆中的学生 - SpeakingMax英语口语达人

Would it focus your attention on making sure you did the things ? that were most important to you?

你会不会把注意力都放在保证自己,做的都是对自己来说最重要的事情？

耶鲁公开课 - 死亡课程节选