方法按随机、双盲、安慰剂对照严格设计，对乙型肝炎疫苗接种11年后效果及免疫记忆进行观察。
Methods The study was strictly designed with randomization, double blinding, and placebo controlled method to observe the efficacy and immune memory 11 years following hepatitis B vaccination.
评价接种酵母重组乙肝疫苗（基因疫苗）的免疫效果与免疫持久性，为基因疫苗的推广应用及高危新生儿乙型肝炎的预防提供依据。
To assess the immunogenecity and efficacy of the yeast recombinant hepatitis B vaccine (YHB vaccine) for the prevention of hepatitis B in the newborns.
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