泛素缀合途径参与细胞的多种代谢过程,包括DNA损伤修复、细胞周期调控及应激反应等。
The ubiquitin-conjugating pathway involves in numerous metabolic processes in cells, including DNA damage repair, cell cycle control, stress responses and so on.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
乳腺癌易感基因,BRCA1,编码一种E3泛素连接酶,BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
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