2.3.1 抗血管生成(Anti-giogenesis)药物目前唯一具有抑制血管生成的药物,原先此药物是设计来抗溃疡的,但之后发现另一新作用为抑制胃癌恶化。
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...板聚集抑制; 抗血管生成 [gap=1235]Key words:Agkistrodon acutus venom; Platelet aggregation inhibitor; Angiogenesis; ...
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The results indicate that VEGF may be a potential targeted molecular in the anti-angiogenesis therapy of osteosarcoma.
该结果提示VEGF可以作为骨肉瘤抗血管生成治疗的潜在靶分子。
参考来源 - 骨肉瘤VEGF表达及VEGF抗体抑制血管生成的实验研究Antiangiogenic therapy, although effective ininhibiting tumor growth, has not been shown tumoricidal in most studies.
不过,抗血管生成疗法虽然在抑制肿瘤生长方面有效,但许多研究结果表明其并不直接杀死肿瘤细胞。
参考来源 - 小鼠PNASBackground:American scholar Folkman the first time give the well-known doctrine:“tumor growth is dependent on tumor angiogenesis”. And putting forward a new way-anti-angiogenesis to inhibit tumor growth.
研究背景:1971年,美国学者Folkman首先提出“肿瘤生长依赖血管生成”的著名学说,并由此提出了抑制肿瘤生长的新途径-抗血管生成(antiagiogensis)。
参考来源 - 血管内皮生长因子受体1在大肠杆菌中的表达与纯化·2,447,543篇论文数据,部分数据来源于NoteExpress
抗血管生成治疗已经成为治疗恶性血液疾病的重要策略。
The generation and development of hematological malignancies are close related to vasculogenesis, so it is an important tactic of anti-vessel growth therapy in hematological malignancies.
因此对健康组织来说,抗血管生成药物能引起广泛和非预期的副作用。
Thus, drugs that target critical angiogenesis molecules can cause a wide range of unintended side effects in healthy tissue.
内皮抑素是一种抗血管生成的抑制因子,它特异性地作用于新生微血管的内皮细胞,其水平与肿瘤血管生成有着明显的相关性。
Endostatin is a kind of angiogenesis inhibitor, specific effecting in the new microvascular endothelial cells. The level of endostatin and the angiogenesis of tumor have a close correlation.
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