抗菌后效应（PAE)：指停药后，抗生素在机体内的浓度低于最低抑菌浓度MIC或者被机体完全清除，细菌在一段时间内仍处于持续受抑制状态。
抗菌后效应的存在提示药物对细菌作用的时间应为血药浓度高于MIC的时间与PAE时间之和。
PAE suggest that the sum of drug effective time is a combination of PAE and the time that anti-microbial concentration above the MIC in blood.
方法：讨论抗菌药物后效应、时间依赖性和浓度依赖性抗菌药物以及细菌耐药问题与合理使用抗菌药物的关系。
Method: Discuss the relations between the rational use of antimicrobial agents and the post effect, time dependence, concentration dependence, resistent of antimicrobial agents.
目的：探讨氟喹诺酮类抗菌药后效应及其合理应用。
OBJECTIVE:To probe into the after-effects and rational use of fluroquinoloncs.
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