抗原变异分为抗原漂移(antigenic drift )和抗原漂变(antigenic shift),抗原漂移:指由基因组发生突变导致抗原的小幅度变异,不产生新的亚型,属于量变,没有质的变化。多引起流感的中小型流行。抗原漂变:流感病毒抗原发生的大幅度或彻底的变异现象。
这种抗原变异(antigenic variation)现象也见于恶性疟原虫寄生的红细胞表面。抗原伪装(antigenic disguise)是寄生虫体表结合有宿主的抗原,例如血吸虫肺期童虫结合...
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抗原变异 antigenic variation ; antigenic evolution ; antigen variation ; antigenic variance 癌抗原 SCCAg ; CA ; Cancer antigen ; squamous cell carcinoma antigen ..
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It is very difficult to develop ideal vaccine providing protection against all subtypes of AIV, for the highly frequent antigenic variation of HA and NA gene of AIV.
AIV最大的特点是亚型众多、抗原变异频繁,因而研制一种能够防制所有亚型的AI疫苗是极为困难的。
参考来源 - 表达禽流感病毒HAThe genetic evolution and antigenic variation rule of influenza A viruses were explored. Valuable clues were provided for the prevention and control of influenza.
通过本研究,对上海地区近年来人群甲型流感病毒的抗原进化和基因进化过程有了直观的理解,同时深入了解了其抗原变异和基因变异的规律,为防控流感提供了有价值的线索。
参考来源 - 上海地区人群甲型流感HA抗原进化与基因进化关系研究及H1N1流感潜在免疫显性位点的筛选·2,447,543篇论文数据,部分数据来源于NoteExpress
流感病毒抗原变异与流感的流行大小、预防、控制密切相关。
The antigenic variation of flu virus is closely related to the epidemic situations, the precaution, and the control of flu.
这种模型包含了两种竞争,第一种导致了假性标志的出现,这种现象被称为原始抗原变异。
The model includes two forms of competition. The first form leads to a phenomenon known as deceptive imprinting, or original antigenic sin.
Kumar参加了一个由多个医院协作的研究项目,旨在找出其答案。初步结果显示,病症的严重性与HLA(人白细胞抗原系统,一种免疫系统内的基因变异)有关。
Kumar is coordinating a multi-hospital study of severe H1N1 to find out, but says preliminary results suggest severity is linked to HLA, a genetic variation in immune systems.
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