免疫系统的一个新的婴儿需要时间来成熟和产生抗体。

The immune system of a new baby takes time to mature and to produce antibodies .

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在抗体发育的最后阶段，抗体生成B细胞识别病原体的特定部分，然后变异或者成熟，所以抗体可以结合病原体更加牢固。

In the final stage of antibody development, antibody-producing B cells recognize specific parts of a pathogen and then mutate, or mature, so the antibody can bind to the pathogen more firmly.

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该方法体外模拟了抗体亲和力成熟的过程，使得到的抗体不但可以完全的人源化，而且可以具有较高的亲和力。

Because this method was to simulate the process of antibody maturation in vivo, the obtained antibodies was not only fully humanized but also with relatively high affinity.

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That's shown here, a B-cell gets stimulated, matures into an antibody producing factory.

这里展示的是,当一个B细胞被激活,分化成熟为一个生成抗体的工厂

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If you looked later, as the antibody production response matures, some IgG is produced so that in the late period after initial priming you'd have a mixture of IgM and IgG in the blood.

如果你稍后再观察,等到产生抗体的应答趋于成熟后,就会产生一些IgG抗体,在初次免疫的最终阶段,你的血液中有IgM,和IgG两种抗体

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Now, these Th-cells, helper T-cells, go on to stimulate B-cells, and it's these B-cells that become the mature antibody producing cells that make quantities of antibody that fill up in your body.

这些辅助性T细胞,进一步刺激B淋巴细胞,从而使这些B淋巴细胞,逐渐发育成成熟的抗体生成细胞,可在体内产生大量抗体

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