由于移植物抗宿主病病情的严重性,临床医生在治疗中,往往缺乏细致诊断,就使用大剂量的类固醇抑制免疫细胞的反应。
Because of the severity of GVHD, clinicians often begin treatment — high doses of steroids to suppress the immune response — in the absence of a concrete diagnosis.
结果:辅助性肝脏移植患者免疫抑制剂浓度相对较低,排斥反应次数少,强度低。
Results:Immunosuppressive agent concentration was lower, rejection was less and intensity was milder in these patients.
结论异种移植发生延迟性排斥反应时,P选择素和ICAM - 1均有表达,可以作为判断异种移植免疫抑制治疗效果的指标之一。
Conclusion the expression of P-selectin and ICAM-1 in xenografts was increased during delayed xenograft rejection, which is of value in judging the effect of immunosuppression in xenotransplantation.
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