结果:二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用,但抑制细胞的分化。
Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.
而周期性拉伸刺激对成骨细胞的分化、矿化起抑制作用。
Then cyclic stretching inhibited differentiation and mineralization of osteoblasts at all loaded time.
结论LPS刺激骨组织发生炎症反应、抑制成骨细胞分化。
Conclusion LPS could involve bone tissue in inflammation and inhibit the differentiation of osteoblast.
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