直接方法主要采用手性流动相添加剂(Chiral Mobile Phase Additives,CMPA)法和手性固定相(CSP)法。CMPA法又可称为手性流动相(CMP)拆分法或手性洗脱法。
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手性流动相添加剂法 CMPA
法和手性流动相添加剂 CMPA ; Chiral Mobile Phase Additive
和手性流动相添加剂 Chiral Mobile Phase Additive
The chiral separations of Mannich enantiomers were studied by using Vancomycin (Chirobiotic V) and Cellulose (Sumichiral OA 2500s) Chiral Stationary Phase (CSP), Chiral Mobile Phase Additive (CMPA) and Chiral Ligand-Exchange Chromatography (CLEC) in this study.
本文研究了应用大环抗生素类万古霉素手性固定相(Chirobiotic V)法和纤维素类手性固定相(Sumichiral OA 2500s)法，手性流动相添加剂法和手性配体交换色谱法分离曼尼希碱类活性化合物对映异构体。
参考来源 - 几个曼尼希碱化合物对映异构体的HPLC手性分离分析研究·2,447,543篇论文数据，部分数据来源于NoteExpress
目的：建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。
Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.
本论文的第三至第六部分介绍了高效液相色谱手性流动相添加剂法拆分麻黄碱、对羟基苯甘氨酸甲酯、美托洛尔、布洛芬对映体。
In part III to VI, ephedrine, tyrosine methyl ester, metoprolol, ibuprofen enantiomeric separation with chiral additive as mobile phase by high performance liquid chromatography are presented.
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