关键词:阿奇霉素;成盐剂;稳定性;肝脏毒性 [gap=1135]KEY WORDS Azithromycin; Salt forming agents; Stability test; Hepatic toxicity
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目的选择适合的注射用阿奇霉素成盐剂。
Objective To select the appropriate salt being used for azithromycin for injection.
结论谷氨酸、天冬氨酸均为合适的阿奇霉素成盐剂。
Conclusion Glutamic acid and aspartic acid are the appropriate acid for the preparation for azithromycin for injection.
以水为溶剂，取代芳磺酸为拆分剂，用诱导结晶法，经成盐、拆分、水解过程，将DL-对羟基苯甘氨酸拆分成D-对羟基苯甘氨酸。
The resolution of DL p hydroxyphenylglycine into its D and L isomers was studied by using aromatic sulfonic acid as resolving agent and water as solvent.
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