目的建立成牙本质细胞样细胞体外培养体系，观察体外培养的牙髓细胞向成牙本质细胞分化过程中细胞周期的变化。

Objective to investigate the differentiation of dental pulp cells into odontoblast-like cells correlates with the changes of cells proliferation.

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新分化的成牙本质细胞样细胞发生极化。

The odontoblast-like cells were in polarization.

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结论：FGF18可能促进小鼠成牙本质细胞的增殖和分化。

Conclusion: FGF18 may play a role during the development of dental germ and could improve the proliferation and differentiation of odontoblast.

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