拷贝数分析显示肿瘤具有异质性，具有异源性分化的恶性叶状肿瘤有不同的肿瘤演化。
Copy number analysis revealed intratumoral heterogeneity and evidence for divergent tumor evolution in malignant phyllodes tumors with and without heterologous differentiation.
本研究结果表明， 新的通路参与恶性叶状肿瘤的发病机制，显著提高了我们对肿瘤生物学的认识，具有潜在的临床意义。
The results identify novel pathways involved in the pathogenesis of malignant phyllodes tumors, which significantly increase our understanding of tumor biology and have potential clinical impact.
我们测序了10例恶性叶状肿瘤的510个癌症相关基因，其中5例伴有脂肪肉瘤样分化，1例伴有粘液软骨肉瘤样分化。
We sequenced 510 cancer-related genes in 10 malignant phyllodes tumors, including 5 tumors with liposarcomatous differentiation and 1 with myxoid chondrosarcoma-like differentiation.
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