目的研究压力超负荷时心肌闰盘的变化。
Objective To investigate the change of intercalated discs induced by pressure overload.
结果：正常小鼠心肌中未见穿孔素阳性表达，连接蛋白43在心肌闰盘中呈阳性表达。
Results in normal mice, perforin was negative and connexin 43 was located in the intercalated disks of cardiac muscle.
结果术后10周手术组心肌闰盘的粘着膜、桥粒、间隙连接结构模糊，连接间隙增宽；
Results At the 10th week after constriction, the structure of cadherin, desmosome and gap junction in intercalated discs were destroyed, gap of intercellular space widened.
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