目的采用家兔心肌缺血再灌注损伤动物模型,观察缺血预适应对心肌缺血再灌注损伤的心肌保护作用。
Objective To observe the protective effect of ischemic preadaptation on myocardium injury of ischemia reperfusion by adopting the animal model of ischemia reperfusion on myocardium injury rabbits.
目的:从细胞保护角度出发,研究缺血预适应对家兔心肌缺血再灌注损伤的保护作用,并探讨其机制。
Objective: to explore research the protective effect of ischemia preconditioning to rabbits 'myocardium injury of ischemia reperfusion, and discuss its mechanism.
缺血预适应是指心脏遭受短暂缺血后能耐受随后较长时间缺血损伤,是近年发现的一种预防心肌缺血损伤的有效措施。
Ischemic preconditioning has been defined as a tolerance of the myocardium to subsequent sustained ischemic damage after the heart was insulted one or more brief periods of ischemic stress.
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