事实上，试图与季节的变更做斗争是一种让人精疲力竭而且有时徒劳无益的工作。
Striving to resist the inturning of the season can be an exhausting and sometimes futile undertaking.
博士及学位都是徒劳无益的，除非你的工作能荣耀神。
推动两种文化以一种建设性的方式共同工作的努力常常徒劳无益。
It is often a Sisyphean endeavor to get the two cultures to work together in a constructive manner.
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