结论:异种血管内皮生长因子基因重组T7噬菌体疫苗可打破机体对自身vegf的免疫耐受,诱导产生较高水平的特异性抗vegf抗体。
Conclusion: Recombinant T7 phage vaccine expressing xenogenic VEGF can break immunologic tolerance against self-VEGF and induce the producing of specific anti-VEGF antibody.
本发明涉及一种制备异多聚体多肽如双特异性抗体、双特异性免疫粘附素和抗体—免疫粘附素嵌合体的方法。
The invention relates to a method of preparing heteromultimeric polypeptides such as bispecific antibodies, bispecific immunoadhesins and antibody-immunoadhesin chimeras.
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