细胞到达靶器官、识别移植的异体抗原，启动一系列变化。

The T cell arrives at the target organ, the recognition transplant foreign body antigen, starts a series of changes.

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结果自体角质形成细胞可抑制淋巴细胞对同种异体抗原的增殖。

Methods The mixed epidermal cell and lymphocyte culture (MELC) was established, in which auto-keratinocytes were added to mimic the effect exerted by the auto-islets in vivo.

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在过去的50年里，啮齿动物模型已经成为人们用来阐明针对同种（异体）抗原免疫耐受机制的极有价值的工具。

Over the past 50 years, rodent models have become an invaluable tool for elucidating the mechanisms of tolerance to alloantigens.

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