目的合成巴柳氮二钠并改进工艺。
OBJECTIVE To synthesize balsalazide disodium and optimize the process.
方法以对硝基苯甲酰氯为起始原料，经缩合、 还原、重氮化、偶合、成盐等反应制得巴柳氮二钠。
METHODS Balsalazide disodium was synthesized by reactions of condensation , reduction, diazotization , coupling and salification from 4-nitrobenzoyl chloride.
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