盐酸左旋西替利嗪是西替利嗪的活性光学异构体，是UCB公司首先于2001年在德国上市的第三代抗过敏药物，它用药量少，毒副作用较西替利嗪小，而继承了西替利嗪起效快、抗过敏作用强的特性，在体内很少被代谢，药物的相互作用较少，是理想的H1受体拮抗剂，是西替利嗪的替代品。能用于6岁以上儿童，而脱羧氯雷他定只能用于12岁以上儿童。
以苯甲酰氯为原料，经酰化，还原，环合等反应合成左旋西替利嗪盐酸盐，反应总收率为8.05%。
Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation, hydrogenation, cyclization with an overall yield of 8.05%.
以苯甲酰氯为原料，经酰化，还原，环合等反应合成左旋西替利嗪盐酸盐，反应总收率为8。05%。
Levocetirizine dihydrochloride was prepared from benzoyl chloride by acids lation hydrogenation cyclization with an overall yield of8.05%.
论文通过三条路线，经化学拆分法或手性诱导合成法，对左旋西替利嗪及其中间体的合成进行了研究。
Three synthetic routes to prepare levocetirizine and its intermediates through chemical resolution and chiral induction were studied in the paper.
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