目的:完善和规范基因剔除小鼠技术体系的关键技术环节,建立一套高效的嵌合体制备体系。
Objective: To establish a highly efficient production system of chimeras by perfecting and normalizing the key steps of technology system of gene knockout mice.
嵌合体由两种或两种以上有不同基因结构的组织所构成的有机体,由于突变、嫁接或来自不同合子的细胞群体相混合而产生。
An organism consisting of two or more tissues of different genetic composition, produced as a result of mutation, grafting, or the mixture of cell populations from different zygotes.
遗传上混合的胚胎甚至被科学家都称作凯米拉(基因嵌合体),源自古希腊神话的一种狮头,羊身,蛇尾的吐火的妖怪。
Genetically mixed embryos are referred to even by scientists as chimeras, after a monster from ancient Greek mythology. Perhaps that shows a lack of public-relations nous.
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