这就为以医疗装置对疾病负担的影响为基础来确定选购重点带来了挑战。

This creates challenges to establish priorities in the selection of medical devices on the basis of their impact on the burden of disease.

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随着越来越多的国家使用诊断检测方法对疟疾进行确诊，在实际看到真实的疾病负担及集中地方面，我们将不再盲目开展工作。

With more countries using diagnostic tests to confirm malaria, we are no longer working in the dark in terms of actually seeing the real disease burden and where it is concentrated.

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这些往往是疾病负担最大、人口十分贫穷、对可靠药物的需求也最大的国家。

These are often the countries with the highest burden of disease, the poorest populations and the greatest need for reliable medicines.

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