三苯氧胺会诱发或加重绝经期症状，但可减少对侧乳腺癌的发生率，降低血清胆固醇。
Tamoxifen can induce or exacerbate menopausal symptoms but reduces incidence of contralateral breast cancer and lowers serum cholesterol.
目的在BRCA1和BRCA2基因表达阳性的家族成员中评估对侧乳腺癌的发病风险，以明确预测风险因子。
Purpose to estimate the risk for contralateral breast cancer in members of BRCA1 - and BRCA2-positive families and to determine predictive risk factors.
目的：探讨发生双侧乳腺癌的相关因素和对预后的影响。
Objective: to study relative factors and prognostic effects of occurrence of double sides primary breast cancer.
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