由于移植物抗宿主病病情的严重性,临床医生在治疗中,往往缺乏细致诊断,就使用大剂量的类固醇抑制免疫细胞的反应。
Because of the severity of GVHD, clinicians often begin treatment — high doses of steroids to suppress the immune response — in the absence of a concrete diagnosis.
镜下,移植物抗宿主反应是说明“程序性细胞死亡”或单个细胞坏死(即调亡)过程的最好例子。
Microscopically, graft versus host disease is one of the best examples of a process called "apoptosis" or single cell necrosis.
宿主的免疫系统可能反应过激并且杀死太多细胞,这可能是这个病毒更具致病力的关键因素。
The host's immune system may be overreacting and killing off too many cells, and that may be a key contributor to what makes this virus more pathogenic.
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