传统的实验设计与分析方法为首先进行正交实验设计，然后对实验结果进行回归分析和方差分析以确定最佳工艺条件。
Traditional methods for experiment design and analysis is to design orthogonal experiment first, and then make regression analysis and variance analysis to search the optimal technological condition.
这些结果的统计显著性与不同的因子有关，从实验设计到统计检验。
The statistical significance of these results is related to different factors, from the experimental design to the statistical tests.
结果：两种实验设计中对照组与病例组基因型和等位基因频率差异均无统计学意义。
Results:There were no significant differences in the genotype and allele frequencies between cases and controls.
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